Summary: Amgen and Ideaya Biosciences are winding down their cancer combination study involving PRMT5 inhibitor AMG 193 and MAT2A inhibitor IDE397. Ideaya will continue to explore MAT2A-PRMT5 combinations with its in-house PRMT5 inhibitor, IDE892, focusing on non-small cell lung cancer.
Full articleSummary: Amgen and Ideaya Biosciences are winding down their cancer combination study involving their PRMT5 inhibitors, leading to the termination of their collaboration. Meanwhile, Ideaya plans to focus on testing its PRMT5 inhibitor, IDE892, with MAT2A inhibitor IDE397 in non-small cell lung cancer patients.
Full articleSummary: IDEAYA Biosciences announced a clinical study collaboration and supply agreement with Gilead Sciences to evaluate IDE397 in combination with Trodelvy in NSCLC, updates expected in 2025, actively enrolling patients in various trials. Stock price is up by 3.78% in pre-market hours.
Full article